Clark Wellness, PLLC - Functional Medicine, Weight Control and IV therapy
Autoimmunity & Inflammation

Immune & Inflammatory Conditions

When the immune system loses self-tolerance, suppressing symptoms is only half the battle.

At Clark Wellness, we investigate the root triggers of autoimmune disease and chronic inflammation—including gut permeability (leaky gut), molecular mimicry from stealth infections, food reactivity, and environmental toxin overload.

Immune system balance and autoimmune care

The Autoimmune Triad

According to Functional Medicine research, autoimmune disease requires three factors: genetic susceptibility, an environmental trigger (virus, toxin, stress), and intestinal permeability (leaky gut). By healing the gut barrier and removing triggers, we restore immune balance.

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Conditions We Treat

Immune Disorders & Inflammatory Syndromes

Autoimmune Diseases

Lupus, Rheumatoid Arthritis, Psoriasis, Celiac, Sjogren's, and Hashimoto's thyroiditis.

Long COVID / Long-Haul COVID

Persistent fatigue, brain fog, shortness of breath, palpitations, and joint pain lasting months after acute infection — driven by viral persistence, immune dysregulation, and microvascular inflammation.

Chronic Fatigue Syndrome (ME/CFS)

Profound exhaustion accompanied by post-exertional malaise and mitochondrial dysfunction.

Fibromyalgia & Chronic Pain

Widespread musculoskeletal pain, tender points, and heightened nervous system pain sensitivity.

Histamine Intolerance & MCAS

Mast Cell Activation Syndrome causing unexplained flushing, hives, racing heart, or food reactions.

Recurrent Infections

Frequent sinus infections, EBV reactivations, or persistent susceptibility to seasonal bugs.

High Inflammatory Biomarkers

Elevated hs-CRP, ESR, or ANA levels that standard labs fail to explain.

Clinical Strategy

Re-educating the Immune System

Our goal is not merely immune suppression, but immune modulation—helping your body regain tolerance and dampening auto-antibody flares.

Immune system balance and modulation

Advanced Antibody & Gut Testing

Utilizing Cyrex array testing, Gut Zoomer intestinal permeability panels, and comprehensive food reactivity profiles.

Anti-Inflammatory Nutrition

Personalized Autoimmune Protocol (AIP), Low-Histamine, or Elimination diets with 1:1 health coaching guidance.

Targeted Immunomodulation

Nutaceuticals like Curcumin, Resveratrol, Omega-3s, SPM resolvins, and Low-Dose Naltrexone (LDN) when appropriate.

Ready to calm autoimmune flares and regain your vitality?

Schedule a discovery call with Angelica Clark, PA-C, IFMCP.

Advanced Diagnostics

Autoimmune Zoomer® by Vibrant Wellness

A comprehensive blood test that detects autoantibodies against 26+ tissue antigens — revealing hidden autoimmune activity years before symptoms escalate and standard labs turn positive.

Multi-Tissue Autoantibody Screen

Detects autoantibodies to 26+ organs and tissues — including thyroid, brain, joints, gut, heart, skin, kidneys, and pancreas — for a full-body autoimmune map.

Early Detection, Before Damage

Identifies elevated autoantibodies in the subclinical stage — often years before conventional ANA or disease-specific panels register a problem.

Brain & Neural Tissue Markers

Screens for autoantibodies to neural antigens linked to brain fog, anxiety, depression, and neuroinflammation driving Long COVID symptoms.

Gut Barrier & Food Reactivity

Evaluates antibodies tied to intestinal permeability (leaky gut), celiac, and cross-reactive foods that fuel immune activation.

Thyroid & Endocrine Autoimmunity

Measures autoantibodies to thyroid tissue and endocrine organs — catching Hashimoto's, Graves', and adrenal autoimmunity early.

Joint, Cardiac & Skin Targets

Assesses autoantibodies to collagen, cardiac tissue, and skin antigens — relevant for rheumatoid, lupus, psoriasis, and cardiovascular inflammation.

Viral & Infection Triggers

Helps connect autoimmune flares to viral triggers such as EBV, SARS-CoV-2 (Long COVID), and other stealth infections that ignite immune dysregulation.

Mitochondrial Autoantibodies

Detects antibodies against mitochondria — a key driver of the profound fatigue and post-exertional malaise seen in Long COVID and ME/CFS.

Personalized Immune Roadmap

Results guide a targeted protocol — removing triggers, healing the gut barrier, and modulating the immune system instead of blanket suppression.

Why We Trust Autoimmune Zoomer® for Immune & Long COVID Care

Autoimmune conditions — including Long COVID — rarely start in the tissue being attacked. They begin with a trigger, a leaky gut barrier, and an immune system that has lost self-tolerance. Autoimmune Zoomer® gives Angelica Clark, PA-C, IFMCP a precise, full-body antibody map so she can calm the immune response at its source instead of chasing symptoms one organ at a time.

Google Reviews

Google Reviews

5.0
(110 reviews)
View on Google
SH

Stephanie Hofer

September 29, 2026

Google

Functional medicine at its best! Angelica is extremely knowledgeable and digs for the root of the issues, not just temporary fixes. The extensive testing gave us clear answers we couldn't get anywhere else.

P

Parvitas

September 24, 2026

Google

Just wanted to add my name to the growing list of extremely satisfied patients Angelica and staff have been able to treat over the years. Truly exceptional care, compassionate staff, and protocols that actually work.

MM

Melissa Martinez

August 7, 2026

Google

Love this process!!! Best health decision I have ever made.

AK

A K

June 10, 2026

Google

I so appreciate the expertise and care that Angelica Clark and the Clark Wellness Waco Team - Shaun and Savannah - have shown me over the past year after being dismissed by multiple doctors. They truly partner with you to be the best you.

RS

Rachel Shaver

May 8, 2026

Google

Anjelica is wonderful! She has helped me tremendously in a short amount of time with an autoimmune disease I suffer from. Her expertise in natural healing and functional testing is unmatched.

RG

Rebecca Griffith

April 13, 2026

Google

Incredibly knowledgeable and caring. I finally feel heard and have real answers after years of being dismissed by other clinics. The team is warm and truly supportive.

WV

Wendy Varner

April 3, 2026

Google

Angelica and her team are a blessing! They take the time to listen, explain every lab value in depth, and craft a plan that fits real life.

JN

Jennifer Niemann

February 17, 2026

Google

Such a great experience from beginning to end with life-changing results!!!! I feel like myself again for the first time in years.

LR

Lisa Ray

February 9, 2026

Google

Great people... Wonderful place! Thorough, professional, and genuinely caring healthcare that gets to the root cause.

MH

Melody Hadden

February 6, 2026

Google

I love Angelica and her team! I've lost 35lbs in 3 months so far and my energy levels are higher than they have been in a decade.

RS

Riley Scroggins

November 14, 2025

Google

Worth every penny! I felt seen and heard as a patient and loved that the goal was to get to the root cause and treat it as a whole. Incredibly kind and thorough.

MAD

Mary Ann Davison

November 12, 2025

Google

Incredibly knowledgeable… helped pinpoint hormonal imbalances and nutrient deficiencies that traditional blood panels missed.

PW

Pam Weldon

October 31, 2025

Google

So thankful for Angelica's guidance and compassionate approach. She is always prepared and responsive.

CS

Chase Sodolak

October 29, 2025

Google

Great staff that genuinely care and take the time to get to know you on a personal level. Highly recommend to anyone searching for real wellness.

MLB

Ms. Lee Bock

October 25, 2025

Google

I could not have asked for something better. They are my saving grace. Six months ago, I did not care if I lived or died. I had been to several other doctors with no answers. Angelica gave me my life back.

LA

Leticia Anzaldua

October 22, 2025

Google

After a year of visiting Angelica I feel like never before, now I know how to stay healthy and free from major diseases. I feel so blessed that I met Angelica and Savannah. They always make me feel at home.

MW

Marie Weller

September 18, 2025

Google

Great staff, Angelica is very professional, caring, and knowledgeable as is her staff also.

JG

Jennifer Garner

September 16, 2025

Google

Best healthcare I have ever received. Think of it. A physician that actually listens to the patient!