Mood, Brain & Sleep
When your brain feels foggy, anxious, or unable to rest, the root cause is rarely just in your head.
At Clark Wellness, we look at the neuro-endocrine matrix—investigating how gut inflammation, hormone shifts, cortisol imbalances, and nutrient deficiencies affect your neurotransmitters, mood, focus, and sleep architecture.

The Gut-Brain & Sleep Connection
Did you know that over 90% of your body's serotonin is produced in the digestive tract, and melatonin is regulated by your 24-hour cortisol curve? Restoring brain power starts with healing the whole body.
Explore Functional Medicine TestingSymptoms We Address
We treat the whole person, mapping out how systemic factors drive cognitive and emotional distress.
Anxiety & Mood Swings
Unexplained nervousness, irritability, panic, or emotional dysregulation tied to blood sugar or progesterone drops.
Depression & Low Motivation
Feeling flat, unmotivated, or emotionally drained due to chronic neuroinflammation or dopamine depletion.
Insomnia & Sleep Disruptions
Trouble falling asleep, waking up at 2–3 AM with a racing heart, or non-restorative sleep.
Brain Fog & Memory Issues
Difficulty concentrating, word-finding troubles, or slow processing speed caused by gut permeability or mold toxicity.
How We Investigate Neuro-Endocrine Balance
Instead of relying solely on mood-altering prescriptions, we search for the underlying biochemical triggers.

Organic Acids & Neurotransmitters
Evaluating dopamine, serotonin, and norepinephrine metabolites (HVA, 5-HIAA, VMA) along with vitamin B6 and folate pathways.
24-Hour Melatonin & Cortisol Curve
DUTCH test analysis measuring night-time melatonin production and HPA axis dysfunction to repair sleep architecture.
Gut-Brain Axis & Microbiome
Screening for SIBO, Candida yeast, leaky gut permeability, and neuroinflammatory LPS endotoxins via Gut Zoomer stool analysis.
Ready to reclaim your sleep, focus, and emotional resilience?
Schedule a consultation with Angelica Clark, PA-C, IFMCP.
Neuro Zoomer® by Vibrant Wellness
A high-resolution blood test that detects autoantibodies to neural tissue — revealing hidden neuroinflammation, blood-brain barrier disruption, and autoimmune brain activity that standard psychiatry workups never measure.
Neural Autoantibodies
Screens for autoantibodies against myelin basic protein (MBP), myelin oligodendrocyte glycoprotein (MOG), synapsin, and cerebellar antigens — markers of immune attack on brain tissue.
Blood-Brain Barrier Integrity
Evaluates antibodies to S100B and other barrier proteins to detect breakdown of the protective lining that keeps toxins and immune cells out of the brain.
Neurotransmitter Receptors
Measures autoantibodies to dopamine, NMDA, GABA, and serotonin receptors that can drive anxiety, depression, mood swings, and cognitive dysfunction.
Glutamate & Excitotoxicity
Assesses antibodies related to glutamate receptor activity — elevated excitotoxicity is linked to brain fog, insomnia, anxiety, and neurodegeneration.
GAD65 & Blood Sugar-Brain Link
Detects GAD65 autoantibodies connecting blood-sugar dysregulation and insulin resistance to mood instability and panic-like symptoms.
Aquaporin-4 & Neuroinflammation
Screens AQP4 antibodies associated with neuroinflammatory conditions that can present as fatigue, brain fog, and sleep disruption.
Synapsin & Neural Plasticity
Evaluates synapsin autoantibodies affecting neurotransmitter release, synaptic repair, learning, memory, and cognitive resilience.
Tubulin & Axonal Health
Measures alpha & beta tubulin autoantibodies reflecting damage to nerve fibers and impaired communication between brain regions.
Amphiphysin & Nerve Signaling
Detects amphiphysin autoantibodies linked to disrupted nerve signaling, sensory changes, and autonomic nervous system imbalance.
Why We Trust Neuro Zoomer® for Mood, Brain & Sleep
Anxiety, depression, brain fog, and insomnia are often driven by immune-mediated neuroinflammation — not a neurotransmitter shortage. Neuro Zoomer® gives Angelica Clark, PA-C, IFMCP a precise map of your brain's immune activity so she can build a targeted protocol instead of guessing with another prescription.
Google Reviews
Stephanie Hofer
September 29, 2026
Functional medicine at its best! Angelica is extremely knowledgeable and digs for the root of the issues, not just temporary fixes. The extensive testing gave us clear answers we couldn't get anywhere else.
Parvitas
September 24, 2026
Just wanted to add my name to the growing list of extremely satisfied patients Angelica and staff have been able to treat over the years. Truly exceptional care, compassionate staff, and protocols that actually work.
Melissa Martinez
August 7, 2026
Love this process!!! Best health decision I have ever made.
A K
June 10, 2026
I so appreciate the expertise and care that Angelica Clark and the Clark Wellness Waco Team - Shaun and Savannah - have shown me over the past year after being dismissed by multiple doctors. They truly partner with you to be the best you.
Rachel Shaver
May 8, 2026
Anjelica is wonderful! She has helped me tremendously in a short amount of time with an autoimmune disease I suffer from. Her expertise in natural healing and functional testing is unmatched.
Rebecca Griffith
April 13, 2026
Incredibly knowledgeable and caring. I finally feel heard and have real answers after years of being dismissed by other clinics. The team is warm and truly supportive.
Wendy Varner
April 3, 2026
Angelica and her team are a blessing! They take the time to listen, explain every lab value in depth, and craft a plan that fits real life.
Jennifer Niemann
February 17, 2026
Such a great experience from beginning to end with life-changing results!!!! I feel like myself again for the first time in years.
Lisa Ray
February 9, 2026
Great people... Wonderful place! Thorough, professional, and genuinely caring healthcare that gets to the root cause.
Melody Hadden
February 6, 2026
I love Angelica and her team! I've lost 35lbs in 3 months so far and my energy levels are higher than they have been in a decade.
Riley Scroggins
November 14, 2025
Worth every penny! I felt seen and heard as a patient and loved that the goal was to get to the root cause and treat it as a whole. Incredibly kind and thorough.
Mary Ann Davison
November 12, 2025
Incredibly knowledgeable… helped pinpoint hormonal imbalances and nutrient deficiencies that traditional blood panels missed.
Pam Weldon
October 31, 2025
So thankful for Angelica's guidance and compassionate approach. She is always prepared and responsive.
Chase Sodolak
October 29, 2025
Great staff that genuinely care and take the time to get to know you on a personal level. Highly recommend to anyone searching for real wellness.
Ms. Lee Bock
October 25, 2025
I could not have asked for something better. They are my saving grace. Six months ago, I did not care if I lived or died. I had been to several other doctors with no answers. Angelica gave me my life back.
Leticia Anzaldua
October 22, 2025
After a year of visiting Angelica I feel like never before, now I know how to stay healthy and free from major diseases. I feel so blessed that I met Angelica and Savannah. They always make me feel at home.
Marie Weller
September 18, 2025
Great staff, Angelica is very professional, caring, and knowledgeable as is her staff also.
Jennifer Garner
September 16, 2025
Best healthcare I have ever received. Think of it. A physician that actually listens to the patient!
